Clinical Trials in Cardiology - S

Maintained by Dr. Olga Shindler. Last update on February 27, 2001.

Alphabetic list:
A / B / C / D / E / F / G / H / I / J / K / L / M /
N / O / P / Q / R / S / T / U / V / W / X / Y / Z /

4S
Scandinavian Simvastatin Survival Study
(a) Am J Cardiol 1993;71:393-400
(b) Lancet 1994;344:1383-1390
(c) Am J Cardiol 1995;76:64C-68C
(d) Lancet 1995;345:1274-1275
(e) Arch Intern Med 1996;156:2085-2092
(f) PharmacoEconomics 1996;9:101-105
(g) Eur Heart J 1996;17:1001-1007
(h) circulation 1997;96:4211-4218
(i) N Engl J Med 1997;336:332-336
(j) Circulation 1998;97:1453-1460
(k) Am J Cardiol 1998;81:333-335

4S (Substudy)
Scandinavian Simvastatin Survival Study
Ann Intern Med 1999;59:2661-2667

SABER
Stent Assisted Balloon angioplasty: its Effects on Restenosis

SAC
Splinting for Acute Closure

SADS
Sudden Adult Death Survey

SAECG
Signal Averaged ElectroCardioGraphic studies

SAFE
Safety After Fifty Evaluation
(a) Am Heart J 1988;116:301-4
(b) J Am Geriatr Soc 1992;40:354-8

SAGES
Signal AveraGed Electrocardiographic Study

SAHCS
Streptokinase Aspirin Heparin Collaborative Study

SAHS
San Antonio Heart Study

SAK
Studie Asymptomatische Karotisstenose

SALAD
Surgery vs Angioplasty for proximal Left Anterior Descending coronary artery stenosis

SALT
Swedish Aspirin in Low-dose Trial
Lancet 1991;338:1345-9

SAMI
Streptokinase Angioplasty Myocardial Infarction trial
(a) J Am coll Cardiol 1991;19(suppl A):336A
(b) Circulation 1992;86:1710-1717

SAMII
Survey of Acute Myocardial Ischemia and Infarction

SAMIT
Streptokinase Angioplasty Myocardial Infarction Trial

SAMMEC
Smoking-Attributable Mortality, Morbidity, and Economic Cost study

SAMPLE
Study on Ambulatory Monitoring of Pressure and Lisinopril Evaluation

SAPAT
Swedish Angina Pectoris Aspirin Trial
Lancet 1992 Dec 12;340(8833):1421-5.

SAS
Scandinavian Angiopeptin Study

SASS
Sygen Acute Stroke Study

SAT
Saruplase Alteplase Trial

SATSA
Swedish Adoption,/Twin Study of Aging

SATT
Scottish Adjuvant Tamoxifen Trial

SAVE
Survival And Ventricular Enlargement
(a) JAMA 1991;266:528-532
(b) Am J Cardiol 1991;68:70D-79D
(c) N Engl J Med 1992;327:669-677
(d) Circulation 1994;90:1731-1738
(e) Circulation 1997;96:3294-3299

SAVED
SAphenous VEin De novo
N Engl J Med 1997;337:740-747

SBCS
Stockholm Breast Cancer Study

SCA&I
registry of the Society for Cardiac Angiography and Interventions

SCAMP
Stanford Coronary Artery Monitoring Project

SCAR
Severe Cutaneous Adverse Reaction study

SCAT
Simvastatin and enalapril Coronary Atherosclerosis Trial
Can J Cardiol 1997 Jun;13(6):591-9
Circulation 2000 Oct 10;102(15):1748-54

SCATI
Studio sulla Calciparina nell'Angina e nella Trombosi ventricolare nell'Infarto
Lancet 1989;ii:182-6

SCD-HeFT
Sudden Cardiac Death in Heart Failure: Trial of prophylactic amiodarone versus implantable defibrillator therapy

SCETI
Stanford Computer-based Educator Training Intervention

SCIC
Sopravvivenza con Captopril nell'Insufficienza Cardiaca

SCIV
SubCutaneous vs IntraVenous heparin in deep venous thrombosis

SCOPE
Surveillance and Control Of Pathogens of Epidemologic importance

SCOR
Specialized Centers Of Research programs, e.g., UCSF arteriosclerosis intervention trial

SCPS
Skin Cacer Prevention Study

SCRIP
Stanford Coronary Risk Intervention Project
(a) Circulation 1991;84(suppl 2):11-140
(b) Circulation 1994 Mar;89(3):975-90
(c) J Am Coll Cardiol 1994 Oct;24(4):900-8

SCRIPPS
Scripps Coronary Radiation to Inhibit Proliferation Post Stenting

SCS
Seven Country Study

SDIS
Stockholm Diabetes Intervention Study

SECORDS
SouthEasthern Consortium On Racial Differences in Stroke

SECP
Sequential External Counter Pulsation study

SECURE
Study to Evaluate Carotid Ultrasound changes with Ramipril and vitamin E
(a) Am J Cardiol 1996 Oct 15;78(8):914-9
(b) Circulation 2001 Feb 20;103(7):919-925

SELCA
Smooth Excimer Laser Coronary Angioplasty study

SEMIUC
Sociedad Espanola Medicina Intensive y Unidades Coronarias survey

SENDCAP
St. Mary's Ealing, Northwick Park Diabetes CArdiovascular Prevention study

SENIC
Study on the Efficacy of Nosocomial Infection Control

SEPIVAC
Studio EPidemiologico sull'Incidenza delle Vasculopatie Acute Cerebrali

SEPS
Submaximal Exercise Performance Substudy

SEPSIS
Studio Epidemiologico Policentrico Sulla Incidenza della Sepsi

SEQOL
Study of Economics and Quality Of Life

SESAIR
Studio Eparina Sottocutanea nell'Angina Instabile Refrattaria
Lancet 1995;345:1201-1204

SESAM
Study in Europe of Saruplase and Alteplase in Myocardial infarction
Am J Cardiol 1997 Mar 15;79(6):727-32

SFCP
Standford Five City Project

SHAPE
Stress, Health, And Physical Evaluation program

SHAPE
Study of Heparin and Actilyse Processed Electronically
Br Heart J 1991;66:62

SHARP
Subcutaneous Heparin and Angioplasty Restenosis Prevention
J Am Coll Cardiol 1995 Oct;26(4):947-54

SHAVE
Steerable Housing for Athero Vascular Excision

SHELL
Systolic Hypertension in the Elderly Long-term Lacidipine trial
J Cardiovasc Pharmacol 1994;23(suppl 5):S62-66

SHEP
Systolic Hypertension in the Elderly Program
(a) JAMA 1991;265:3255-64
(b) Hypertension 1991;17(suppl 2):II-1-171
(c) Control Clin Trials 1993;14:350-61
(d) J Am Geriatr Soc 1994;42:1143-9
(e) JAMA 1996;276:1886-1892
(f) JAMA 1997;278:212-216
(g) JAMA 1998;279:778-780
(h) Arch Intern Med 1998;158:741-751

SHEP
Systolic Hypertension in the Elderly Program
Dementia and Disability Outcomes in Large Hypertension Trials:
Lessons Learned from the Systolic
Am J Epidemiol 2001 Jan 1;153(1):72-78

SHEP
Systolic Hypertension in the Elderly Program
Serum uric acid, diuretic treatment and risk of cardiovascular events in the
Systolic Hypertension in the Elderly Program (SHEP)
J Hypertens 2000 Aug;18(8):1149-54

SHEP
Systolic Hypertension in the Elderly Program
Effect of treating isolated systolic hypertension on the risk of developing various
types and subtypes of stroke: the Systolic Hypertension in the Elderly Program (SHEP)
JAMA 2000 Jul 26;284(4):465-71

SHEP
Systolic Hypertension in the Elderly Program
Clinical trials in isolated systolic hypertension
Curr Hypertens Rep 1999 Oct;1(5):387-93

SHHS
Scottish Heart Health Study


SHIPS
SHIga Pravastatin Study

SHOCK
SHould we emergently revascularize Occluded Coronaries for cardiogenic shocK?
(a) N Eng J Med 1999;341:625-634
(b) J Am Coll Cardiol. 2000 Sep;36(3 Suppl A)
(c) JAMA 2001 Jan 10;285(2):190-192

SHOCK
SHould we emergently revascularize Occluded Coronaries for cardiogenic shocK?
Diabetes mellitus in cardiogenic shock complicating acute myocardial infarction: a report from the SHOCK Trial Registry.
J Am Coll Cardiol. 2000 Sep;36(3 Suppl A):1097-103.

SHOT
SHunt Occlusion Trial

SHP
Skaraborg Hypertension Project

SHS
Strong Heart Study

SHVRC
Shiley Heart Valve Research Center projects

SIAC
Studio Indobufene Angioplastica Coronarica

SIAM
Streptokinase In Acute Myocardial infarction
J Am Coll Cardiol 1990;15(suppl A):63A

SICCO
Stenting in Chronic Coronary Occlusion
J Am Coll Cardiol 1996;28:1444-1451
J Am Coll Cardiol 1998 Aug;32(2):305-10

SIESTA
Snooze-Induced Excitation of Sympathetic Triggered Activity study

SIFA
Studio Italiano nella Fibrillazione Atriale

SIHDSPS
Stockholm Ischemic Heart Disease Secondary Prevention Study

SIMAP
Studio Italiano Multicentrico Angina Pectoris

SINBA
Studio Indobufene Net Bypass Aortocoronarico

SIRS
Systemic Inflammatory Response Syndrome study

SISAMI
Silent lschemia in Survivors of Acute Myocardial lnfarction

SISTEMI
Southern Italian Study on Thrombolysis Early in Myocardial lnfarction

Sixty-Plus Reinfarction Study
Lancet 1980;ii:989-94

SKDAMI
StreptoKinase plus Desmopressin in Acute Myocardial lnfarction

SLIP
Studio Lipidi Isoptin Press
Drugs 1993;46:(suppl 2):16-23

SLS
Seattle Longitudinal Study

SLVDS
San Luis Valley Diabetes Study

SMART
Stimulation Medullaire et ARTeriopathie

SMART
Study of Medicine vs Angioplasty Reperfusion Trial
J Am Coll Cardiol 1994;(suppl):225A

SMART
Study of Micro-stent's Ability to limit Restenosis Trial

SMASH
Swiss Multicenter evaluation of Angioplasty for Shock following myocardial infarction

SMILE
So Much Improvement with a Little Exercise program

SMILE
Survival of Myocardial Infarction: Long-term Evaluation
(a) Ann Ital Med Int 1993;8:230-4
(b) Control Clin Trials 1994;15:210-10
(c) N Engl J Med 1995;332:80-5

SMISS
Silent Myocardial Ischemia Stress Study

SMOG
Studio Multicentrico Ospedaliero Gallopamil

SMS
Simvastatin Multicenter Study

SMT
Spanish Multicenter Trial

SMT
Stockholm Metoprolol Trial
(a) J Am Coll Cardiol 1985;5:1428-37
(b) Eur Heart J 1986;7:312-9
(c) Acta Med Scand 1986;220:33-8
(d) Eur Heart J 1988;9:365-72

SNaP
Study of Sodium and blood Pressure

SNAP
Score for Neonatal Acute Physiology

SOF
Study of Osteoporotic Fractures in association with strokes

SOLVD
Studies Of Left Ventricular Dysfunction
(a) Am J Cardiol 1990;66:315-322
(b) N Engl J Med 1991;325:293-302
(c) Am J Cardiol 1991;68:1465-8
(d) N Engl J Med 1992;327:685-91
(e) J Am Coll Cardiol 1994;23:393-400
(f) Am J Cardiol 1995;75:1244-9
(g) Circulation 1995;91:2573-81
(h) J Card Fail 1995;1:371-80
(i) Am Heart J 1996 Feb;131(2):350-5.
(j) J Am Coll Cardiol 1998 Sep;32(3):695-703.
(k) N Eng J Med 1999;340:609-616
(l) Am J Cardiol 1999 Aug 1;84(3):252-7.
(m) Am Heart J 1999 Nov;138(5 Pt 1):849-55.
(n) J Am Coll Cardiol 2000 Apr;35(5):1237-44
(o) J Heart Lung Transplant. 2000 Jun;19(6):598-608

SOLVD
Studies Of Left Ventricular Dysfunction
Shindler DM, Kostis JB, Yusuf S, Quinones MA, Pitt B, Stewart D, Pinkett T, Ghali JK, Wilson AC.
Diabetes mellitus, a predictor of morbidity and mortality in the Studies of Left Ventricular
Dysfunction (SOLVD) Trials and Registry.
Am J Cardiol. 1996 May 1;77(11):1017-20

SOLVD
Studies Of Left Ventricular Dysfunction
Kostis JB, Shelton B, Gosselin G, Goulet C, Hood WB, Kohn RM, Kubo SH, Schron E, Weiss MB, et al.
Adverse effects of enalapril in the Studies of Left Ventricular Dysfunction (SOLVD).
SOLVD Investigators.
Am Heart J. 1996 Feb;131(2):350-5

SOLVD
Studies Of Left Ventricular Dysfunction
Greenberg B, Quinones MA, Koilpillai C, Limacher M, Shindler D, Benedict C, Shelton B.
Effects of long-term enalapril therapy on cardiac structure and function in patients with left
ventricular dysfunction. Results of the SOLVD echocardiography substudy.
Circulation. 1995 May 15;91(10):2573-81.

SOS
Swedish Obesity Surgery study

SPAA
Studio sulla Pressione Arteriosa nell'Anziano
Eur Heart J 1992;13:178-82

SPAF
Stroke Prevention in Atrial Fibrillation
(a) N Engl J Med 1990;322:863-8
(b) Circulation 1991;84:527-39

SPAF II
Stroke Prevention in Atrial Fibrillation II
(a) Lancet 1994;343:687-91
(b) Lancet 1994;343:1508-9

SPAF III (Substudy)
Stroke Prevention in Atrial Fibrillation
Jama 1998;279:1273-1277

SPAF III TEE
Stroke Prevention in Atrial Fibrillation III TransEsophageal Echo study
(a) Eur Heart J 1994;15:(abstr suppl):28
(b) Eur Heart J 1996;17:1129
(c) Lancet 1996;348:633-638

SPARCL
Stroke Prevention by Aggressive Reduction in Cholesterol Levels

SPEED
Stratigies for Patency Enhancement in the Emergency Department
Circulation 2000 Jun 20;101(24):2788-94

SPI
Study of Perioperative Ischemia

SPIC
Studio Policentrico Italiano Cardiomiopatie
II Cuore 1994;11:187-93

SPINAF
Stroke Prevention in Nonrheumatic Atrial Fibrillation
N Engl J Med 1992;327:1406-12

SPRINT-2
Secondary Prevention Reinfarction Israel Nifedipine Trial 2 study
Arch Intern Med 1993;153:345-353

SPIR
Study of Perioperative Ischemia Research

SPIRIT
Salvage from Perindopril In Reperfused Infarction Trial

SPIRIT
Stroke Prevention In Reversible Ischemia Trial
Stroke 1997;28:231

SPORE Specialized Programs Of Research Excellence

SPORT
Stent implantation POst Rotational atherectomy Trial

SPRINT
Secondary Prevention Reinfarction Israeli Nifedipine Trial
Eur Heart J 1988;9:354-64

SPRINT II
Secondary Prevention Reinfarction Israeli Nifedipine Trial II
Arch Intern Med 1993;153:345-53

SPRS
Sixty Plus Reinfarction Study

SPRT
Sixty Plus Reinfarction Trial

SPS
Stockholm Prospective Study

SPT
Single Patient Trial

SPT Stent PAMI Trial
ACC meetings - March 1998 Atlanta,Georgia

SQUID
Superconducting QU antum Interference Devices study in fetal cardiology

SRT
Sorbinil Retinopathy Trial

SSSD
Spanish Study on Sudden Death
Am J Cardiol 1993;72:1243-8

SSSS
Scandinavian Simvastatin Survival Study
(a) Am J Cardiol 1993;71:393-400
(b) Lancet 1994;344:1383-1390
(c) Am J Cardiol 1995;76:64C-68C
(d) Lancet 1995;345:1274-1275
(e) Arch Intern Med 1996;156:2085-2092
(f) PharmacoEconomics 1996;9:101-105
(g) Eur Heart J 1996;17:1001-1007
(h) circulation 1997;96:4211-4218
(i) N Engl J Med 1997;336:332-336
(j) Circulation 1998;97:1453-1460
(k) Am J Cardiol 1998;81:333-335

STAI
Studio della Ticlopidina nell'Angina Instabile
Circulation 1990;82:17-26

STAI
Study of Ticlopidine in Angor Instable

STAMI
Stenting for Acute Myocardial Infarction

STAMP
Systemic Thrombolysis in Acute Myocardial infarction with
Prourokinase and urokinase
(a) Eur Heart J 1989;10(suppl):124
(b) J Am Coll Cardiol 1990;15(suppl A):3A

Stanford Five-City Project
Am J Epidemiol 1990;132:629-46

STAR
SCVIR Transluminal Angioplasty and Revascularization study

STAR
STAphylokinase Recombinant trial

STAR
Study of Tranexamic acid after Aneurysm Rupture

STARC
Studio Trapidil vs Aspirin nella Restenosi Coronarica
Circulation 1994;90:2710-5

STARS
St. Thomas' Atherosclerosis Regression Study
J Cardiovasc Pharmacol 1995;25:(suppl 4):S11-19

STARS (3 Anti-thrombotics)
Stent Anticoagulation Regimen Study
N Eng J Med 1998;339:1665-1675

STARS
Stent Antithrombotic Regimen Study

START
St.Thomas' Atherosclerosis Regression Trial

START
Saruplase and Taprostene Acute Reocclusion Trial
Eur Heart J 1993;14:1118-1126

START
Study of Thrombolytic therapy with Additional Response following Taprostene

START
Stent Vs Directional Coronary Atherectomy Randomized Trial
J Am Coll Cardiol 1999;34:1050-1057

START (Stenting vs PTCA)
Stent Implantation and Balloon Angioplasty in the Treatment of De Novo Coronary Artery Lesions
J Am Coll Cardiol 1999;34:1498-1506

STARTS
STent Anti-Thrombotic Regimen Study

STAT
Stroke Treatment with Ancord Trial
Jama 2000;283:2395-2403

Stent PAMI Trial
Stent Primary Angioplasty in Myocardial Infarction Study
N Eng J Med 1999;341:1949-1956

STENTIM
STENTing In acute Myocardial infarction

STEP
Simultaneous Transmission - Emission Protocol

STEP
STudio Embolia Polmonare

STEP
Study of Taprostene in Elective PTCA

STEPS
Significance of Transesophageal Echocardiographic findings in
Prevention of Stroke study

STEPHY
Stamberg Trial on Epidemiology of Parkinsonism and HYpertension in the elderly

STILE
Surgery vs Thrombolysis for Ischemic Lower Extremity
Ann Surg 1994;220:251-68

STIMS
Swedish Ticlopidine Multicenter Study
(a) J Intern Med 1990;227:301-8(erratum 228:659)
(b) Eur J Vasc Endovasc Surg 1995;10:69-76

STIPAS
Safety study of Tirilazad mesylate In Patients with Acute ischemic Stroke

STONE
Shanghai Trial Of Nifedipine in the Elderly
J Hypertens 1996;14:1237-45

STOP
Shunt Thrombatic Occlusion prevention by Picotamide

STOP-Hypertension
Swedish Trial in Old Patents with Hypertension
(a) Cardiovasc Drug Ther 1990;4:1253-6
(b) Lancet 1991;338:1281-5
(c) Clin Exp Hypertens 1993;15:925-39
(d) J Intern Med 1993;234:317-23

STOP-Hypertension II
Swedish Trial in Old Patents with Hypertension 2 Ongoing trial
(a) Blood Press 1993;2:136-41
(b) Blood Press 1996;5:300-4

STOP-Hypertension II (Update)
Swedish Trial in Old Patents with Hypertension 2 Ongoing trial
Lancet 1999;354:1751-1756

STOP IT
Sites Testing Osteoporosis Prevention Intervention Treatment

STRATAS
Study To determine Rotational And Transluminal Angiography Strategy

STRATUS
Study to determine Rotablator And TranslUminal angioplasty Strategy

STRESS
STent REStenosis Study
(a) N Engl J Med 1994;331:496-501
(b) Am J Cardiol 1998;81:860-865

STRETCH
Symptom, Tolerability, Response to Exercise Trial of Candesartan Cilexetil in Heart Failure
Circulation 1999;100:2224-2230

STRIP
Special Turku coronary Risk factor Intervention Project for babies
Am J Clin Nutr 2000 Nov;72(5 Suppl):1316S-31S

STRUT
Stent Treatment Region assessed by Ultrasound Tomography

SUPPORT
Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatment

SURE
Serial Ultrasound analysis of Restenosis trial

SUTAMI
Saruplase and Urokinase in Treatment of Acute Myocardial lnfarction
Fibrinolysis 1993;7:330-4

SUVIMAX
SUpplementation VItamin Minerals and AntioXidant trial

SVTS
Sotalol Ventricular Tachycardia Study

SWEET
Square Wave Endurance Exercise Trial

SWIFT
Should We Intervene Following Thrombolysis trial
(a) BMJ 1991;302:555-60
(b) Br Med J 1991;302:555-560

SWISH
Swedish Isradipine Study in Hypertension
J Cardiovasc Pharmacol 1991;18:(suppl 3):S7-8

SWISSI
SWiss Interventional Study on Silent Ischemia

SWISSI II
SWiss International Study on Silent Ischemia II ongoing trial
Circulation 1995;692(suppl 1):1-80

SWORD
Surveillance of Work-related and Occupational Respiratory Disease

SWORD
Survival With ORal D-sotalol
(a) Am J Cardiol 1995;75:1023-7
(b) Lancet 1996;348:7-12
(c) Am J Cardiol 1998;81:869-876

SYMPHONY
Sibrafiban vs aspirin to yield maximum protection from ischemic heart events
post acute coronary syndromes
Lancet 2000;355:337-345

SYMPHONY 2
Sibrafiban vs aspirin to Yield Maximum Protection from ischemic Heart events
post acute coronary syndromes

SYST-CHIN
SYSTolic hypertension in elderly CHINese trial
Curr Hypertens Rep 1999 Oct;1(5):387-93

SYST-CHINA
SYSTolic hypertension in elderly CHINese triAl
(a) J Hum Hypertens 1996;10(suppl 1):S9-11
(b) J Hum Hypertens 1996;10:735-42
(c) Curr Hypertens Rep 1999 Oct;1(5):387-93

SYST-EUR
SYSTolic hypertension in elderly in EURope trial
(a) Aging 1991;3:287-302
(b) Fam Pract 1996;13:138-43

SYST-EUR
SYSTolic Hypertension-EURope
Lancet 1997;350:757-764

SYST-EUR
SYSTolic hypertension in elderly in EURope trial
Treatment of diabetic patients with hypertension
Curr Hypertens Rep 1999 Jun;1(3):225-31

SYST-EUR
SYSTolic hypertension in elderly in EURope trial
Effects of calcium channel blockade in the older patients with
diabetes and systolic hypertension
N Eng J Med 1999;340:677-684

SYST-EUR
SYSTolic hypertension in elderly in EURope trial
Effects of antihypertensive treatment on endpoints in the diabetic patients
randomized in the Systolic Hypertension in Europe (Syst-Eur) trial
J Nephrol 2000 May;13(3):232-7.

SYST-EUR
SYSTolic Hypertension-EURope
Serum uric acid, diuretic treatment and risk of cardiovascular
events in the Systolic Hypertension in the Elderly Program (SHEP)
J Hypertens 2000 Aug;18(8):1149-54

Alphabetic list:
A / B / C / D / E / F / G / H / I / J / K / L / M /
N / O / P / Q / R / S / T / U / V / W / X / Y / Z /

e-mail:shindler@umdnj.edu
Copyright © 1995-2001 Dr. Olga Shindler.